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Oral and Other Non-Insulin Hypoglycemic Agents


Insulin secretagogues#

Stimulate beta cells to increase insulin secretion. ÔÜá´ŞĆMay result in hypoglycemia.#


Sulfonylureas#

Tolbutamide#

  • Orinase┬«

Glimepiride#

  • Amyral┬«

Glipizide#

  • Glucotrol┬«
  • Glucotrol XL┬«

Glyburide#

  • Micronase┬«, DiaBeta┬«

Glyburide, micronized#

  • Glynase PresTab┬«

Glinides#

Repaglinide#

  • Prandin┬«

Nateglinide#

  • Starlix┬«

Euglycemics#

Brings the blood glucose into the normal range. Low risk of hypoglycemia.#


Metformin#

  • Glucophage┬«
  • Extended release (ER):
    • Glucophage XR┬«
    • Fortamet┬«
    • Glumetza
  • Riomet┬« (liquid, 500 mg/5ml)

Alpha-glucosidase inhibitors#

Delays digestion and absorption of carbohydrates. Low risk of hypoglycemia.#


Acarbose#

  • Precose┬«

Thiazolidinediones (Glitazones or TZDs)#

Decreases insulin resistance in fat and muscle tissues. Low risk of hypoglycemia.#


Pioglitazone#

  • Actos┬«

Rosiglitazone#

  • Avandia┬«

Albiglutide#

  • Tanzeum┬«

GLP-1 (glucagone-like peptide-1) analogs#

Increases insulin secretion, reducess glucose release from liver after meals, delays food emptying from stomach and promotes satiety. Low risk of hypoglycemia. (These medications are also known as incretin mimetics.)#


Exenatide#

  • Byetta┬«

Liraglutide#

  • Victoza┬«

Dulaglutide#

  • Trulicity┬«

DPP-4 (dipeptidyl peptidase-4) inhibitors#

Increases insulin secretion and reduces glucose release from the liver after meals, Low risk of hypoglycemia.#


Alogliptin#

  • Nesina┬«

Sitagliptin#

  • Januvia┬«

Saxagliptin#

  • Onglyza┬«

    Linagliptin#

  • Tradjenta┬«

SGLT2 (sodium-glucose co-transporter-2 ) inhibitors#

Increases glucose excretion in the urine. Low risk of hypoglycemia.#


Canagliflozin#

  • Invokana┬«

Dapagliflozin#

  • Farxiga┬«

Empagliflozin#

  • Jardiance┬«

Combination oral medications#


Alogliptin/Metformin#

  • Kazano┬«

Alogliptin/Pioglitazone#

  • Oseni┬«

Empagliflozin/Linagliptin#

  • Glyxambi┬«

Empagliflozin/Metformin#

  • Synjardy┬«

Canagliflozin/Metformin#

  • Invokamet┬«

Dapagliflozin/Metformin XR#

  • Xigduo XR┬«

Glipizide/Metformin#

  • Metaglip┬«

Glyburide/Metformin#

  • Glucovance┬«

Linagliptin/Metformin#

  • Jentadueto┬«

Pioglitazone/Glimepiride#

  • Duetact┬«

Pioglitazone/Metformin#

  • ActoPlus Met┬«

Pioglitazone/Metformin XR#

  • ActoPlus Met XR┬«

Repaglinide/Metformin#

  • PrandiMet┬«

Rosiglitazone/Glimepiride#

  • Avandryl┬«

Rosiglitazone/Metformin#

  • Avandamet┬«

Saxagliptin/Metformin XR#

  • Kombiglyze XR┬«

Sitagliptin/Metformin#

  • Janumet┬«

Sitagliptin/Metformin#

  • Janumet XR┬«

Related Pages#

References/Websites#