Skip to main content

Local Anesthetic Overdose/Toxicity

Signs and symptoms#

Early (1-5 minutes after injection)

  • light headedness
  • dizziness
  • disorientation
  • drowsiness
  • visual and auditory disturbances (tinnitus, difficulty focusing)
  • metallic taste

Late

  • muscle twitching
  • convulsions
  • unconsciousness
  • coma
  • respiratory distress and arrest
  • cardiovascular depression and collapse

Action#

Causes#

  • excess dose of local anesthetic
  • inadvertent intravascular injection of local anesthetic

References/Websites#