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CD4 Cell Count

  • CD4 cells are a subset of T lymphocytes (helper T cells), which are part of the body’s defense against fungal, viral, and parasitic infections and exhibit some control over neoplastic growth.
  • The normal CD4 cell count range is approximately 500 – 1500 cells/mm³.
  • A drop in CD4 cell count indicates immune system deterioration.
  • A CD4 cell count below 200 cells/mm³ is considered severe immune suppression.
  • When the CD4 cell count drops below 200 cells/mm³, a patient will start to receive prophylaxis against certain opportunistic infections, such as Pneumocystis jerovecil pneumonia, formerly called Pneumocystis carinii pneumonia (PCP).
  • A CD4 cell count below 200 cells/mm³ is a definition of AIDS.
  • The development of oral lesions is associated with a decreased CD4 cell count.